For analysis of QoL,some questionnaires were developed exclusivelyfor patients with Parkinson’s disease (PD). Thebest known are two scales, Quality of Life Questionnaire (PDQL).Martinez-Martin believes that the qualityParkinson’s Disease. Questionnaire (PDQ-39)and Parkinson’s Disease of life scales aremore useful than other scales in evaluatingthe results of rehabilitation and drugtreatment of Parkinson’s disease or neurosurgery 7. Hence, Parkinson’sDisease Questionnaire- 39 is being used in this study. Therefore, evaluation ofthe severity of any disease should include not only the clinical factors butalso the psychological & social factors pertaining with the patient.Parkinson’s Disease has a profound negative impact on the Quality of Life (QoL)as pointed out by numerous studies, patients suffer from fatigue, dementia,emotional problems, sleep disorders, difficulty in speech and balance,depression, diminished cognitive functions and several other lifestyle changes6. Quality of Life (QoL) isa multi-dimensional construct, which includes at least three main domains:physical, mental and social.
In medicinal sciences, researchers and physicianshave often used health-related quality of life concept, which concentrates onthe impact of the disease and/or treatment on patients’ perception of their lifestyleand on subjective well-being or satisfaction with life 5. Patients are usuallytreated with Levodopa, COMT Inhibitors, Dopamine Agonists, Non-DopaminergicTherapy, etc 3. Therefore, auditing of prescriptions related to the diseaseis essential to increase the therapeutic efficacy and to decrease the sideeffects & also to provide feedback to the prescribers. The main aim ofthis drug utilization study is to facilitate rational drug use and knowing theefficacy of each one of them 4. The rampancy of thedisease ranges from 41 people per 100,000 in the fourth decade of life to morethan 1,900 people per 100,000 among those 80 and older 2.
Parkinson’s disease (PD)is included in a group of neurodegenerative conditions called motor system diseases,which are the result of the loss of dopaminergic brain cells. The primarysymptoms of PD are tremor, or trembling in limbs, jaw, and face rigidity, orstiffness of the limbs and slowness of trunk movement, postural instability, orimpaired balance and coordination 1.